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HMOF/MYST1 Antibody

Product Specifications

Background

The MYST family of histone acetyltransferases, which includes MYST1, is named for the founding members MOZ (MYST3; MIM 601408), yeast YBF2 and SAS2, and TIP60 (HTATIP; MIM 601409) . All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein-protein interactions and targeting transcriptional regulators to chromatin (Neal et al., 2000 [PubMed 10786633]) .[supplied by OMIM].

NCBI Gene ID

84148

Swiss Prot

Q9H7Z6

Accession Number

Q9H7Z6

Host

Rabbit

Reactivity

Human

Immunogen

This HMOF/MYST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-439 amino acids from the C-terminal region of human HMOF/MYST1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

52 kDa

Fragment

Rabbit Ig

Symbol

KAT8

NCBI Official Name

Histone acetyltransferase KAT8

NCBI Organism

Homo sapiens

Background Reference 01

Rea, S., Oncogene 26 (37), 5385-5394 (2007)

Background Reference 02

Pfister, S., Int. J. Cancer 122 (6), 1207-1213 (2008)

Background Reference 03

Gupta, A., Mol. Cell. Biol. 28 (1), 397-409 (2008)

Other Product Names

Histone acetyltransferase KAT8, Lysine acetyltransferase 8, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1, MYST-1, hMOF, KAT8, MOF, MYST1

Tested Applications

WB, IHC-P

Protein ID

68565938

Physical Properties

Liquid

Curated Selection

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