OTOA Antibody
Product Specifications
Background
The protein encoded by this gene is specifically expressed in the inner ear, and is located at the interface between the apical surface of the inner ear sensory epithelia and their overlying acellular gels. It is prposed that this protein is involved in the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in this gene are associated with autosomal recessive deafness type 22 (DFNB22) . Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
NCBI Gene ID
146183
Swiss Prot
Q7RTW8
Accession Number
Q7RTW8
Host
Rabbit
Reactivity
Mouse
Immunogen
This OTOA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-120 amino acids from the N-terminal region of human OTOA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
129 kDa
Fragment
Rabbit Ig
Symbol
OTOA
NCBI Official Name
Otoancorin
NCBI Organism
Homo sapiens
Background Reference 01
Shahin, H., et al. Eur. J. Hum. Genet. 18 (4) :407-413 (2010)
Background Reference 02
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Background Reference 03
Hofmann, O., et al. Proc. Natl. Acad. Sci. U.S.A. 105 (51) :20422-20427 (2008)
Background Reference 04
Zwaenepoel, I., et al. Proc. Natl. Acad. Sci. U.S.A. 99 (9) :6240-6245 (2002)
Other Product Names
Otoancorin, OTOA
Tested Applications
WB, IHC-P
Protein ID
56404568
Physical Properties
Liquid
Curated Selection
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