UROC1 Antibody
Product Specifications
Background
This gene encodes an enzyme involved in histidine catabolism, metabolizing urocanic acid to formiminoglutamic acid. The gene product is known to protect the skin from ultra violet rays and is contained in human sweat. Deficiency of this gene product in the liver is an apparent cause of mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
131669
Swiss Prot
Q96N76
Accession Number
Q96N76
Host
Rabbit
Reactivity
Human
Immunogen
This UROC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-430 amino acids from the Central region of human UROC1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
75 kDa
Fragment
Rabbit Ig
Symbol
UROC1
NCBI Official Name
Urocanate hydratase
NCBI Organism
Homo sapiens
Background Reference 01
Espinos, C., et al. J. Med. Genet. 46 (6) :407-411 (2009)
Background Reference 02
Yamada, S., et al. Oncogene 23 (35) :5901-5911 (2004)
Background Reference 03
Retey, J. Arch. Biochem. Biophys. 314 (1) :1-16 (1994)
Background Reference 04
Kalafatic, Z., et al. Metab. Clin. Exp. 29 (11) :1013-1019 (1980)
Other Product Names
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase, UROC1
Tested Applications
WB, IHC-P
Protein ID
22256789
Physical Properties
Liquid
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