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UROC1 Antibody

Product Specifications

Background

This gene encodes an enzyme involved in histidine catabolism, metabolizing urocanic acid to formiminoglutamic acid. The gene product is known to protect the skin from ultra violet rays and is contained in human sweat. Deficiency of this gene product in the liver is an apparent cause of mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

131669

Swiss Prot

Q96N76

Accession Number

Q96N76

Host

Rabbit

Reactivity

Human

Immunogen

This UROC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-430 amino acids from the Central region of human UROC1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

75 kDa

Fragment

Rabbit Ig

Symbol

UROC1

NCBI Official Name

Urocanate hydratase

NCBI Organism

Homo sapiens

Background Reference 01

Espinos, C., et al. J. Med. Genet. 46 (6) :407-411 (2009)

Background Reference 02

Yamada, S., et al. Oncogene 23 (35) :5901-5911 (2004)

Background Reference 03

Retey, J. Arch. Biochem. Biophys. 314 (1) :1-16 (1994)

Background Reference 04

Kalafatic, Z., et al. Metab. Clin. Exp. 29 (11) :1013-1019 (1980)

Other Product Names

Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase, UROC1

Tested Applications

WB, IHC-P

Protein ID

22256789

Physical Properties

Liquid

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