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ELP3 Antibody

Product Specifications

Background

Elongator complex protein 3 (ELP3) is a catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. It may also have a methyltransferase activity.

NCBI Gene ID

55140

Swiss Prot

Q9H9T3

Accession Number

Q9H9T3

Host

Rabbit

Reactivity

Human

Immunogen

This ELP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 468-498 amino acids from the C-terminal region of human ELP3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

62 kDa

Fragment

Rabbit Ig

Symbol

ELP3

NCBI Official Name

Elongator complex protein 3

NCBI Organism

Homo sapiens

Background Reference 01

Han, Q., Acta Biochim. Biophys. Sin. (Shanghai) 39 (6), 453-461 (2007)

Background Reference 02

Kim, J.H., Proc. Natl. Acad. Sci. U.S.A. 99 (3), 1241-1246 (2002)

Background Reference 03

Ninomiya, Y., J. Biochem. 118 (2), 380-389 (1995)

Other Product Names

Elongator complex protein 3, hELP3, ELP3

Tested Applications

WB, IHC-P

Protein ID

145558902

Physical Properties

Liquid

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