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EMG1 Antibody

Product Specifications

Background

This gene encodes an essential, conserved eukaryotic protein involved in ribosome biogenesis. In yeast, the related protein is a component of the small subunit processome and is essential for biogenesis of the ribosomal 40S subunit. A mutation in this gene has been associated with Bowen-Conradi syndrome.

NCBI Gene ID

10436

Swiss Prot

Q92979

Accession Number

Q92979

Host

Rabbit

Reactivity

Human

Immunogen

This EMG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the Central region of human EMG1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

27 kDa

Fragment

Rabbit Ig

Symbol

EMG1

NCBI Official Name

Ribosomal RNA small subunit methyltransferase NEP1 {ECO:0000305|PubMed:20047967}

NCBI Organism

Homo sapiens

Background Reference 01

Armistead, J., et al. Am. J. Hum. Genet. 84 (6) :728-739 (2009)

Background Reference 02

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Background Reference 03

Lamont, R.E., et al. Am. J. Med. Genet.132A (2), 136-143 (2005) :

Background Reference 04

Bernstein, K.A., et al. Eukaryotic Cell 3 (6) :1619-1626 (2004)

Other Product Names

Ribosomal RNA small subunit methyltransferase NEP1, 211-, 18S rRNA (pseudouridine (1248) -N1) -methyltransferase, 18S rRNA Psi1248 methyltransferase, Nucleolar protein EMG1 homolog, Protein C2f, Ribosome biogenesis protein NEP1, EMG1 {ECO:0000303|PubMed:19463982}

Tested Applications

WB, Flow

Protein ID

20532172

Physical Properties

Liquid

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