ETFA Antibody
Product Specifications
Background
ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
2108
Swiss Prot
P13804
Accession Number
P13804
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This ETFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-304 amino acids from the C-terminal region of human ETFA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=55-652
Calculated Molecular Weight
35 kDa
Fragment
Rabbit Ig
Symbol
ETFA
NCBI Official Name
Electron transfer flavoprotein subunit alpha, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Ohkuma, A., et al. Muscle Nerve 39 (3) :333-342 (2009) Chiong, M.A., et al. Mol. Genet. Metab. 92 (1-2), 109-114 (2007) Olsen, J.V., et al. Cell 127 (3) :635-648 (2006) Olsen, J.V., et al. Cell 127 (3) :635-648 (2006) Schiff, M., et al. Mol. Genet. Metab. 88 (2) :153-158 (2006)
Other Product Names
Electron transfer flavoprotein subunit alpha, mitochondrial, Alpha-ETF, ETFA
Tested Applications
WB, IHC-P, Flow
Protein ID
119636
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
