HTR2B Antibody

Product Specifications

Background

Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets; central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.

NCBI Gene ID

3357

Swiss Prot

P41595

Accession Number

P41595

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This HTR2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-435 amino acids from the C-terminal region of human HTR2B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Neuroscience, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Symbol

HTR2B

NCBI Official Name

5-hydroxytryptamine receptor 2B

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010) Roberts, K.E., et al. Gastroenterology 139 (1) :130-139 (2010) Svejda, B., et al. Cancer 116 (12) :2902-2912 (2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009) Tabakoff, B., et al. BMC Biol. 7, 70 (2009) :