FUT8 Antibody

Product Specifications

Background

This enzyme belongs to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternatively spliced variants encoding different isoforms have been identified.

NCBI Gene ID

2530

Swiss Prot

Q9BYC5

Accession Number

Q9BYC5

Host

Rabbit

Reactivity

Human

Immunogen

This FUT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-357 amino acids from the Central region of human FUT8.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat, Pig, Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

67 kDa

Fragment

Rabbit Ig

Symbol

FUT8

NCBI Official Name

Alpha- (1,6) -fucosyltransferase

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J. Phd, et al. Mol. Med. (2010) In press :

Background Reference 02

Wang, X., et al. J. Biochem. 145 (5) :643-651 (2009)

Background Reference 03

Kudo, T., et al. Mol. Cancer 6, 32 (2007) :

Background Reference 04

Ihara, H., et al. Glycobiology 16 (4) :333-342 (2006)

Other Product Names

Alpha- (1,6) -fucosyltransferase, Alpha1-6FucT, Fucosyltransferase 8, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase, GDP-fucose--glycoprotein fucosyltransferase, Glycoprotein 6-alpha-L-fucosyltransferase, FUT8