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DFNB31 Antibody

Product Specifications

Background

This gene is thought to function in the organization and stabilization of sterocilia elongation and actin cystoskeletal assembly, based on studies of the related mouse gene. Mutations in this gene have been associated with autosomal recessive non-syndromic deafness and Usher Syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

NCBI Gene ID

25861

Swiss Prot

Q9P202

Accession Number

Q9P202

Host

Rabbit

Reactivity

Human

Immunogen

This DFNB31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the Central region of human DFNB31.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

97 kDa

Fragment

Rabbit Ig

Symbol

DFNB31

NCBI Official Name

Whirlin

NCBI Organism

Homo sapiens

Background Reference 01

Letra, A., et al. Am. J. Med. Genet.152A (7), 1701-1710 (2010) :

Background Reference 02

Secolin, R., et al. Psychiatr. Genet. 20 (3) :126-129 (2010)

Background Reference 03

Aller, E., et al. Mol. Vis. 16, 495-500 (2010) :

Background Reference 04

Toiyama, Y., et al. Int. J. Oncol. 35 (4) :709-715 (2009)

Other Product Names

Whirlin, Autosomal recessive deafness type 31 protein, DFNB31, KIAA1526, WHRN

Tested Applications

WB, IHC-P

Protein ID

296453079

Physical Properties

Liquid

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