FGD6 Antibody
Product Specifications
Background
Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain) . May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.
NCBI Gene ID
55785
Swiss Prot
Q6ZV73
Accession Number
Q6ZV73
Host
Rabbit
Reactivity
Human
Immunogen
This FGD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1324-1352 amino acids from the C-terminal region of human FGD6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
161 kDa
Fragment
Rabbit Ig
Symbol
FGD6
NCBI Official Name
FYVE, RhoGEF and PH domain-containing protein 6
NCBI Organism
Homo sapiens
Background Reference 01
Barrios-Rodiles, M., et al. Science 307 (5715) :1621-1625 (2005)
Background Reference 02
Jin, J., et al. Curr. Biol. 14 (16) :1436-1450 (2004)
Other Product Names
FYVE, RhoGEF and PH domain-containing protein 6, Zinc finger FYVE domain-containing protein 24, FGD6, KIAA1362, ZFYVE24
Tested Applications
WB, IHC-P
Protein ID
61213484
Physical Properties
Liquid
Frequently Asked Questions
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