FGD6 Antibody

Product Specifications

Background

Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain) . May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.

NCBI Gene ID

55785

Swiss Prot

Q6ZV73

Accession Number

Q6ZV73

Host

Rabbit

Reactivity

Human

Immunogen

This FGD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1324-1352 amino acids from the C-terminal region of human FGD6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

161 kDa

Fragment

Rabbit Ig

Symbol

FGD6

NCBI Official Name

FYVE, RhoGEF and PH domain-containing protein 6

NCBI Organism

Homo sapiens

Background Reference 01

Barrios-Rodiles, M., et al. Science 307 (5715) :1621-1625 (2005)

Background Reference 02

Jin, J., et al. Curr. Biol. 14 (16) :1436-1450 (2004)

Other Product Names

FYVE, RhoGEF and PH domain-containing protein 6, Zinc finger FYVE domain-containing protein 24, FGD6, KIAA1362, ZFYVE24

Tested Applications

WB, IHC-P

Protein ID

61213484

Physical Properties

Liquid

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