CCNB1 Antibody
Product Specifications
Background
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34 (cdc2) to form the maturation-promoting factor (MPF) . Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq].
NCBI Gene ID
891
Swiss Prot
P14635
Accession Number
P14635
Host
Rabbit
Reactivity
Human
Immunogen
This CCNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 381-411 amino acids from the C-terminal region of human CCNB1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Symbol
CCNB1
NCBI Official Name
G2/mitotic-specific cyclin-B1
NCBI Organism
Homo sapiens
Background Reference 01
Kreis, N.N., et al. Oncogene 29 (41) :5591-5603 (2010)
Background Reference 02
Van Zon, W., et al. J. Cell Biol. 190 (4) :587-602 (2010)
Background Reference 03
Harley, M.E., et al. EMBO J. 29 (14) :2407-2420 (2010)
Background Reference 04
Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Other Product Names
G2/mitotic-specific cyclin-B1, CCNB1, CCNB
Tested Applications
WB, IHC-P
Protein ID
116176
Physical Properties
Liquid
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