Thymidylate Synthase Antibody [2D8.D11]
Product Specifications
Background
Thymidylate synthase (TS) is anintracellular enzyme critical for de novosynthesis of DNA. In cancer, expression of TS is often elevated and becomes further elevated as a result of treatment with the most commonly used chemotherapeutic, 5-fluorouracil (5-FU) . Resistance or lack of response to 5-FU is attributed to the elevation of TS activity. Overexpression of TS has been demonstrated in many types of tumors including breast, colon, gastric and melanoma and is usually predictive of shortened survival time.
NCBI Gene ID
5888
Swiss Prot
Q06609
Accession Number
NP_001157741.1
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human thymidylate synthase produced in E. coli.
Clonality
Monoclonal
Clone
2D8.D11
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Concentration
Batch dependent
Buffer
PBS
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
This antibody is stable for at least one (1) year at -20˚ C. Avoid multiple freeze- thaw cycles.
Fragment
IgG1
Symbol
RAD51
NCBI Official Name
RAD51 recombinase
NCBI Organism
Homo sapiens
Other Product Names
RAD51A, RECA, DNA repair protein RAD51 homolog 1, RAD51 homolog A, HsRAD51, BRCC5, MRMV2, HRAD51, HsRad51, HsT16930
Protein ID
256017143
Physical Properties
Liquid
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