GCH1 Antibody

Product Specifications

NCBI Gene ID

2643

Swiss Prot

P30793

Accession Number

NP_000152.1, NP_001019195.1, NP_001019241.1, NP_001019242.1

Host

Goat

Reactivity

Human

Immunogen

The immunogen for this antibody is: C-GKVHIGYLPNKQ

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction, Neuroscience

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Positive Control

Cat. No. 1314 - Human Thymus Tissue Lysate

Concentration

500 ug/mL

Homology

Expected Species Reactivity based on sequence homology: Mouse, Rat

Buffer

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and store at -20˚ C. Minimize freezing and thawing.

Specificity

This antibody is expected to recognize all four isoforms (NP_000152.1 ; NP_001019195.1 ; NP_001019241.1 ; NP_001019242.1)

Applications Notes

Peptide ELISA: Western Blot:Immunohistochemistry:

Symbol

GCH1

Positive Control 2

Cat. No. 1315 - Human Tonsil Tissue Lysate

Positive Control 3

Cat. No. 1369 - Human Lymph node Tissue Lysate

NCBI Official Name

GTP cyclohydrolase 1

NCBI Organism

Homo sapiens

Background Reference 01

Tegeder I, Costigan M, Griffin RS, Abele A, Belfer I, Schmidt H, Ehnert C, Nejim J, Marian C, Scholz J, Wu T, Allchorne A, Diatchenko L, Binshtok AM, Goldman D, Adolph J, Sama S, Atlas SJ, Carlezon WA, Parsegian A, Lotsch J, Fillingim RB, Maixner W, Geiss GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence. Nat Med. 2006 Nov;12 (11) :1269-77. Epub 2006 Oct 22.