RPE65 Antibody

Product Specifications

NCBI Gene ID

6121

Swiss Prot

Q16518

Accession Number

NP_000320.1

Host

Goat

Reactivity

Rat

Immunogen

The immunogen for this antibody is: C-EVKKNARKAPQPE

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Positive Control

Rat Retina Lysate

Concentration

500 ug/mL

Homology

Expected Species Reactivity based on sequence homology: Human, Dog

Buffer

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and store at -20˚ C. Minimize freezing and thawing.

Applications Notes

Peptide ELISA: Western Blot:

Symbol

RPE65

NCBI Official Name

Retinal pigment epithelium-specific protein 65kDa

NCBI Organism

Homo sapiens

Background Reference 01

Rolling F, Le Meur G, Stieger K, Smith AJ, Weber M, Deschamps JY, Nivard D, Mendes-Madeira A, Provost N, Pereon Y, Cherel Y, Ali RR, Hamel C, Moullier P, Rolling F. Gene therapeutic prospects in early onset of severe retinal dystrophy: restoration of vision in RPE65 Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium. Bull Mem Acad R Med Belg. 2006;161 (10-12) :497-508; discussion 508-9.

Other Product Names

MRPE65, sRPE65, retinal pigment epithelium-specific protein 65kDa, LCA2, RP20, rd12, RBP-binding membrane protein, p63, retinal pigment epithelium-specific 61 kDa protein, retinal pigment epithelium-specific protein (65kD), retinitis pigmentosa 20