PAK1 Antibody

Product Specifications

NCBI Gene ID

5058

Swiss Prot

Q13153

Accession Number

NP_002567.3

Host

Goat

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for this antibody is: C-NTEKQKKKPKMSDE

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Positive Control

Cat. No. 1463 - Rat Brain Tissue Lysate

Concentration

500 ug/mL

Homology

Expected Species Reactivity based on sequence homology: Dog

Buffer

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and store at -20˚ C. Minimize freezing and thawing.

Specificity

No cross-reactivity exptected with PAK3

Applications Notes

Peptide ELISA: Western Blot:

Symbol

PAK1

NCBI Official Name

P21 protein (Cdc42/Rac) -activated kinase 1

NCBI Organism

Homo sapiens

Background Reference 01

Zhao L, Ma QL, Calon F, Harris-White ME, Yang F, Lim GP, Morihara T, Ubeda OJ, Ambegaokar S, Hansen JE, Weisbart RH, Teter B, Frautschy SA, Cole GM. Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease. Nat Neurosci. 2006 Feb;9 (2) :234-42. Epub 2006 Jan 15.

Other Product Names

PAK1, p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast), MGC130000, MGC130001, PAKalpha , p21-activated kinase 1, p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)