MCL1 Antibody

Product Specifications

NCBI Gene ID

4170

Swiss Prot

Q07820

Accession Number

NP_068779.1, NP_001184249.1

Host

Goat

Reactivity

Human

Immunogen

The immunogen for this antibody is: C-AGVGAGLAYLIR

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Positive Control

Cat. No. 1302 - Human Lung Tissue Lysate

Concentration

500 ug/mL

Homology

Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Pig, Cow

Buffer

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and store at -20˚ C. Minimize freezing and thawing.

Specificity

This antibody is expected to recognise reported isoform 1 (NP_068779.1) and isoform 3 (NP_001184249.1) .

Applications Notes

Peptide ELISA: Western Blot:

Symbol

MCL1

Positive Control 2

Cat. No. 1409 - Mouse Thymus Tissue Lysate

Positive Control 3

Cat. No. 1471 - Rat Thymus Tissue Lysate

NCBI Official Name

Myeloid cell leukemia sequence 1 (BCL2-related)

NCBI Organism

Homo sapiens

Background Reference 01

Opferman JT, Letai A, Beard C, Sorcinelli MD, Ong CC, Korsmeyer SJ. Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1. Nature. 2003 Dec 11;426 (6967) :671-6.

Other Product Names

MCL1, TM, EAT, MCL1L, MCL1S, MGC1839, MGC104264, myeloid cell leukemia sequence 1 (BCL2-related), induced myeloid leukemia cell differentiation protein Mcl-1, myeloid cell leukemia sequence 1, myeloid cell leukemia sequence 1, isoform 1, BCL2L3, Mcl-1