LXR Antibody

Product Specifications

NCBI Gene ID

7376

Swiss Prot

P55055

Accession Number

NP_009052.3

Host

Goat

Reactivity

Human

Immunogen

The immunogen for this antibody is: SSPTTSSLDTPLPGC

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Positive Control

Human Bone Marrow Lysate

Concentration

500 ug/mL

Homology

Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog

Buffer

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and store at -20˚ C. Minimize freezing and thawing.

Specificity

Based on the peptide used, this antibody is expected to be specific for LXR beta and not to cross-react with LXR alpha.

Applications Notes

Peptide ELISA: Immunofluorescence: Flow Cytometry: Flow cytometric analysis of HeLa cells. Recommended concentration: 10ug/ml. Flow Cytometry:

Symbol

NR1H2

NCBI Official Name

Nuclear receptor subfamily 1, group H, member 2

NCBI Organism

Homo sapiens

Background Reference 01

Tangirala RK, Bischoff ED, Joseph SB, Wagner BL, Walczak R, Laffitte BA, Daige CL, Thomas D, Heyman RA, Mangelsdorf DJ, Wang X, Lusis AJ, Tontonoz P, Schulman IG. Identification of macrophage liver X receptors as inhibitors of atherosclerosis. Proc Natl Acad Sci USA. 2002 Sep 3;99 (18) :11896-901. Epub 2002 Aug 22.

Other Product Names

NR1H2, LXR-b, NER, UNR, NER-I, RIP15, nuclear receptor subfamily 1, group H, member 2, ubiquitously-expressed nuclear receptor, LXRB, LX receptor beta, liver X receptor beta, liver X receptor-beta, nuclear orphan receptor LXR-beta, oxysterols receptor LXR-beta, steroid hormone-nuclear receptor NER