Insulysin Antibody

Product Specifications

NCBI Gene ID

3416

Swiss Prot

P14735

Accession Number

NP_004960.2, NP_001159418.1, NP_001309722.1, NP_001309723.1, NP_001309724.1, NP_001309726.1

Host

Goat

Reactivity

Human

Immunogen

The immunogen for this antibody is: C-QQYNFDRDNTE

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Positive Control

Cat. No. 1204 - K562 Cell Lysate

Concentration

500 ug/mL

Homology

Expected Species Reactivity based on sequence homology: Dog

Buffer

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and store at -20˚ C. Minimize freezing and thawing.

Specificity

This antibody is expected to recognize all reported isoforms (NP_004960.2; NP_001159418.1; NP_001309722.1; NP_001309723.1; NP_001309724.1; NP_001309726.1) . Reported variants represent identical protein: NP_001309725.1, NP_001309724.1

Applications Notes

Peptide ELISA: Western Blot:Immunohistochemistry:

Symbol

IDE

NCBI Official Name

Insulin-degrading enzyme

NCBI Organism

Homo sapiens

Background Reference 01

Zhao Z, Xiang Z, Haroutunian V, Buxbaum JD, Stetka B, Pasinetti GM. Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease. Neurobiol Aging. 2007 Jun;28 (6) :824-30. Epub 2006 Jun 12.