Cryopyrin Antibody

Product Specifications

NCBI Gene ID

114548

Swiss Prot

Q96P20

Accession Number

NP_004886.3, NP_899632.1, NP_001230062.1, NP_001120933.1, NP_001120934.1

Host

Goat

Reactivity

Human

Immunogen

The immunogen for this antibody is: C-DLYEKAKRDEPK

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

500 ug/mL

Homology

Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Pig, Cow

Buffer

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and store at -20˚ C. Minimize freezing and thawing.

Specificity

This antibody is expected to recognise all five reported isoforms (NP_004886.3; NP_899632.1; NP_001230062.1; NP_001120933.1; NP_001120934.1) . Reported variants represent identical protein (NP_004886.3 and NP_001073289.1) .

Applications Notes

Peptide ELISA: Western Blot:Immunohistochemistry:

Symbol

NLRP3

NCBI Official Name

NLR family, pyrin domain containing 3

NCBI Organism

Homo sapiens

Background Reference 01

Kanneganti TD, Ozoren N, Body-Malapel M, Amer A, Park JH, Franchi L, Whitfield J, Barchet W, Colonna M, Vandenabeele P, Bertin J, Coyle A, Grant EP, Akira S, Nunez G. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature. 2006 Mar 9;440 (7081) :233-6. Epub 2006 Jan 11.

Other Product Names

CIAS1, cold autoinflammatory syndrome 1, AGTAVPRL, AII/AVP, C1orf7, FCAS, FCU, MWS, NALP3, PYPAF1 , AII/AVP receptor-like, Muckle-Wells syndrome, NACHT, LRR and PYD containing protein 3, PYRIN-containing APAF1-like protein 1, angiotensin/vasopressin receptor AII/AVP-like, cryopyrin