Cryopyrin Antibody

Product Specifications

NCBI Gene ID

114548

Swiss Prot

Q96P20

Accession Number

NP_001073289.1, NP_004886.3, NP_899632.1, NP_001120933.1, NP_001120934.1

Host

Goat

Reactivity

Human

Immunogen

The immunogen for this antibody is: C-EKPELTVVFEPSW

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

500 ug/mL

Homology

Expected Species Reactivity based on sequence homology: Rat, Cow

Buffer

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and store at -20˚ C. Minimize freezing and thawing.

Specificity

Variants (NP_001073289.1; NP_004886.3) encode the same isoform.

Applications Notes

Peptide ELISA: Western Blot:Immunofluorescence: Flow Cytometry: Flow cytometric analysis of human peripheral blood monocyte cells. Recommended concentration: 10ug/ml. Flow Cytometry:

Symbol

NLRP3

NCBI Official Name

NLR family, pyrin domain containing 3

NCBI Organism

Homo sapiens

Background Reference 01

Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD. Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet. 2001 Nov;29 (3) :301-5.

Other Product Names

NLRP3, CIAS1, FCU, MWS, FCAS, NALP3, C1orf7, PYPAF1, AII/AVP, AGTAVPRL, CRYOPYRIN, cold autoinflammatory syndrome 1, cryopyrin, Muckle-Wells syndrome, chromosome 1 open reading frame 7, PYRIN-containing APAF1-like protein 1, neuronal apoptosis inhibitor protein 3, angiotensin/vasopressin receptor AII/AVP-like, NLR family, pyrin domain containing 3, AII, AVP, CLR1.1, FLJ95925, AII/AVP receptor-like, NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3, NACHT, LRR and PYD containing protein 3, PYRIN-containing APAF1-like protein 1, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3