SHP-1 Antibody

Product Specifications

NCBI Gene ID

5777

Swiss Prot

P29350

Accession Number

NP_536858.1, NP_002822.2

Host

Goat

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for this antibody is: C-KASRTSSKHKEE

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction, Chemokines & Cytokines

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Positive Control

Cat. No. 1304 - Human Liver Tissue Lysate

Concentration

500 ug/mL

Homology

Expected Species Reactivity based on sequence homology: Dog

Buffer

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and store at -20˚ C. Minimize freezing and thawing.

Specificity

This antibody is expected to recognise both reported isoforms (NP_536858.1and NP_002822.2) . Please note this antibody was designed using the mouse sequence, which differs by 1 amino acid from the human sequence.

Applications Notes

Peptide ELISA: Western Blot:Immunohistochemistry:

Symbol

PTPN6

NCBI Official Name

Protein tyrosine phosphatase, non-receptor type 6

NCBI Organism

Homo sapiens

Background Reference 01

Dubois MJ, Bergeron S, Kim HJ, Dombrowski L, Perreault M, Fournes B, Faure R, Olivier M, Beauchemin N, Shulman GI, Siminovitch KA, Kim JK, Marette A. The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasis. Nat Med. 2006 May;12 (5) :549-56. Epub 2006 Apr 16.

Other Product Names

PTPN6, SHP1, protein tyrosine phosphatase, non-receptor type 6 , HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, 70 kda SHP-1L protein, hematopoietic cell phosphatase, hematopoietic cell protein-tyrosine phosphatase, protein-tyrosine phosphatase 1C