NUMB Antibody

Product Specifications

NCBI Gene ID

8650

Swiss Prot

P49757

Accession Number

NP_001005743.1,001005744.1, NP_003735, NP_001005745.1

Host

Goat

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen for this antibody is: C-PFSSDLQKTFEIEL

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Positive Control

Cat. No. 1403 - Mouse Brain Tissue Lysate

Concentration

500 ug/mL

Homology

Expected Species Reactivity based on sequence homology: Dog, Cow

Buffer

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and store at -20˚ C. Minimize freezing and thawing.

Specificity

This antibody is expected to recognize all reported isoforms (NP_001005743.1, 001005744.1, NP_003735, NP_001005745.1) . It is also likely to cross-react with Numblike (NUMBL, GeneID: 9253) which has a very similar C-Terminus, although this has not yet been tested experimentally.

Applications Notes

Peptide ELISA: Western Blot:Immunofluorescence:

Symbol

NUMB

NCBI Official Name

Numb homolog (Drosophila)

NCBI Organism

Homo sapiens

Background Reference 01

Zhong W, Feder JN, Jiang MM, Jan LY, Jan YN. Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis. Neuron. 1996 Jul;17 (1) :43-53.