Liver X Receptor Antibody

Product Specifications

NCBI Gene ID

10062;7376

Swiss Prot

Q13133

Accession Number

NP_005684.2, NP_009052.3

Host

Goat

Reactivity

Human

Immunogen

The immunogen for this antibody is: CRLQDKKLPPLLSEI

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Homeostasis

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Positive Control

Cat. No. 1306 - Human Spleen Tissue Lysate

Concentration

500 ug/mL

Homology

Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Cow

Buffer

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and store at -20˚ C. Minimize freezing and thawing.

Specificity

This antibody is expected to recognise an epitope corresponding to aa 429-442 of human LXR alpha protein (NP_005684.2) and to aa 443-456 of human LXR beta protein (NP_009052.3) .

Applications Notes

Peptide ELISA: Western Blot:Immunofluorescence:Flow Cytometry:

Symbol

NR1H3; NR1H2

NCBI Official Name

Nuclear receptor subfamily 1, group H, member 3

NCBI Organism

Homo sapiens

Background Reference 01

Tangirala RK, Bischoff ED, Joseph SB, Wagner BL, Walczak R, Laffitte BA, Daige CL, Thomas D, Heyman RA, Mangelsdorf DJ, Wang X, Lusis AJ, Tontonoz P, Schulman IG. Identification of macrophage liver X receptors as inhibitors of atherosclerosis. Proc Natl Acad Sci USA. 2002 Sep 3;99 (18) :11896-901. Epub 2002 Aug 22.

Other Product Names

NR1H3, LXRA, LXR-a, RLD-1, nuclear receptor subfamily 1, group H, member 3, liver X receptor, alpha, NR1H2, NER, UNR, LXR-b, NER-I, RIP15, nuclear receptor subfamily 1, group H, member 2, ubiquitously-expressed nuclear receptor / NR1H2, NER, UNR, LXR-b, NER-I, RIP15, nuclear receptor subfamily 1, group H, member 2, ubiquitously-expressed nuclear receptor, OTTHUMP00000198038, liver X receptor alpha, liver X receptor-alpha, LXRB, LX receptor beta, liver X receptor beta, liver X receptor-beta, nuclear orphan receptor LXR-beta, oxysterols receptor LXR-beta