ADAM12 Antibody

Product Specifications

NCBI Gene ID

8038

Swiss Prot

O43184

Accession Number

NP_003465.3, NP_067673.2

Host

Goat

Reactivity

Human

Immunogen

The immunogen for this antibody is: AARPLPVSPARALC

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Homeostasis

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Positive Control

Cat. No. 1301 - Human Heart Tissue Lysate

Concentration

500 ug/mL

Buffer

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and store at -20˚ C. Minimize freezing and thawing.

Specificity

This antibody is expected to recognise both the longer membrane-bound form of human ADAM12 (NP_003465.3) and the shorter soluble ADAM12 splice isoform (NP_067673.2) . This antibody does not cross-react with other ADAMS.

Applications Notes

Peptide ELISA: Immunohistochemistry:Immunofluorescence: Flow Cytometry: Flow cytometric analysis of HeLa cells. Recommended concentration: 10ug/ml. Flow Cytometry:

Symbol

ADAM12

NCBI Official Name

ADAM metallopeptidase domain 12

NCBI Organism

Homo sapiens

Background Reference 01

Galliano MF, Huet C, Frygelius J, Polgren A, Wewer UM, Engvall E. Binding of ADAM12, a marker of skeletal muscle regeneration, to the muscle-specific actin-binding protein, alpha -actinin-2, is required for myoblast fusion. J Biol Chem. 2000 May 5;275 (18) :13933-9.

Other Product Names

ADAM12, MCMP, MLTN, MLTNA, MCMPMltna, a disintegrin and metalloproteinase domain 12 (meltrin alpha), meltrin alpha, A disintegrin and metalloproteinase domain 12 (Meltrin-alpha, mouse, homolog of), ADAM metallopeptidase domain 12, RP11-295J3.5