Caspase 6 alpha Antibody

Product Specifications

NCBI Gene ID

839

Swiss Prot

P55212

Accession Number

NP_001217.2, NP_116787.1

Host

Goat

Reactivity

Human

Immunogen

The immunogen for this antibody is: NRKVSQRRVDFCKDP

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer

Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

500 ug/mL

Homology

Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Pig, Cow

Buffer

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and store at -20˚ C. Minimize freezing and thawing.

Calculated Molecular Weight

Approx 33kDa

Specificity

This antibody is expected to recognize reproted isoform alpha (NP_001217.2) only. The immunizing peptide overlaps phosphorylated serine 257 and therefore this antibody is not expected to recognize the phosphorylated protein.

Applications Notes

Peptide ELISA: Western Blot:

Symbol

Caspase 6

NCBI Official Name

Caspase 6, apoptosis-related cysteine peptidase

NCBI Organism

Homo sapiens

Background Reference 01

Stanger K, Steffek M, Zhou L, Pozniak CD, Quan C, Franke Y, Tom J, Tam C, Elliott JM, Lewcock JW, Zhang Y, Murray J, Hannoush RN.Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization.