KMO Antibody

Product Specifications

Background

Kynurenine 3-monooxygenase (KMO) catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn) . The enzyme is required for synthesis of quinolinic acid. Quinolinic acid ia a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development.

NCBI Gene ID

98256

Swiss Prot

Q91WN4

Accession Number

EDL13209

Host

Rabbit

Reactivity

Mouse

Immunogen

A synthetic peptide corresponding to an internal region between amino acids 200-299.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Affinity Purified

Concentration

Batch dependent

Modification

None

Shipping Conditions

Dry Ice

Fragment

IgG

Applications Notes

ELISA, Western (immuno) blotting, Immunostaining (in testing)

Symbol

Kmo

NCBI Official Name

Kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)

NCBI Organism

Mus musculus

Background Reference 01

Eniko Vamosa, Arpad Pardutza, Peter Klivenyia, Jozsef Toldib and Laszlo Vecsei, The role of kynurenines in disorders of the central nervous system: Possibilities for neuroprotection. 2009 Journal of the Neurological Sciences Article in Press, Corrected Proof available on line

Other Product Names

317G22.1, KMO_HUMAN, Kynurenine 3 hydroxylase, Kynurenine 3 monooxygenase (kynurenine 3 hydroxylase), Kynurenine 3 monooxygenase, Kynurenine 3-hydroxylase, Kynurenine 3-monooxygenase, RP1-317G22.1, AI046660