KMO Antibody
Product Specifications
Background
Kynurenine 3-monooxygenase (KMO) catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn) . The enzyme is required for synthesis of quinolinic acid. Quinolinic acid ia a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development.
NCBI Gene ID
98256
Swiss Prot
Q91WN4
Accession Number
EDL13209
Host
Rabbit
Reactivity
Mouse
Immunogen
A synthetic peptide corresponding to an internal region between amino acids 200-299.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Affinity Purified
Concentration
Batch dependent
Modification
None
Shipping Conditions
Dry Ice
Fragment
IgG
Applications Notes
ELISA, Western (immuno) blotting, Immunostaining (in testing)
Symbol
Kmo
NCBI Official Name
Kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
NCBI Organism
Mus musculus
Background Reference 01
Eniko Vamosa, Arpad Pardutza, Peter Klivenyia, Jozsef Toldib and Laszlo Vecsei, The role of kynurenines in disorders of the central nervous system: Possibilities for neuroprotection. 2009 Journal of the Neurological Sciences Article in Press, Corrected Proof available on line
Other Product Names
317G22.1, KMO_HUMAN, Kynurenine 3 hydroxylase, Kynurenine 3 monooxygenase (kynurenine 3 hydroxylase), Kynurenine 3 monooxygenase, Kynurenine 3-hydroxylase, Kynurenine 3-monooxygenase, RP1-317G22.1, AI046660
Tested Applications
ELISA, WB, IHC
Protein ID
81879610
Physical Properties
Liquid
Frequently Asked Questions
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