Janus kinase 2 (phospho Tyr972) Antibody
Product Specifications
Background
Janus Kinase 2 (JAK2) is essential for signaling thorough a variety of cytokine receptors. Phosphorylation of JAK is essential for downstream signaling. JAK kinases are known to phosphorylate several substrate including members of the STAT family of proteins
NCBI Gene ID
12643404
Swiss Prot
O60674
Accession Number
BAG63863
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the pY972 region.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Phospho-Specific
Purification
Affinity Purified
Concentration
Batch dependent
Modification
Phospho-Specific
Shipping Conditions
Dry Ice
Fragment
IgG
Applications Notes
ELISA, Western (immuno) blotting, Immunostaining (in testing)
Symbol
JAK2
NCBI Official Name
Janus kinase 2
NCBI Organism
Homo sapiens
Background Reference 01
Issam McDoom, Xianyue Ma, Annet Kirabo, Kuang-Yung Lee, David A. Ostrov and Peter P. Sayeski., Identification of Tyrosine 972 as a Novel Site of Jak2 Tyrosine Kinase Phosphorylation and Its Role in Jak2 Activation., Biochemistry, 2008, 47 (32), pp 8326-8334
Background Reference 02
Parganas E, Wang D, Stravopodis D, Topham DJ, Marine JC, Teglund S, Vanin EF, Bodner S, Colamonici OR, van Deursen JM, Grosveld G, Ihle JN., Jak2 is essential for signaling through a variety of cytokine receptors., Cell. 1998 May 1;93 (3) :385-95
Other Product Names
Janus kinase 2-pY972-phospho specific, Janus kinase 2
Tested Applications
ELISA, WB, IHC
Protein ID
12643404
Physical Properties
Liquid
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