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EGF Antibody (biotin)

Product Specifications

Background

Epidermal growth factor (EGF) has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells. The EGF precursor is believed to exist as a membrane-bound molecule which is proteolytically cleaved to generate the 53-amino acid peptide hormone that stimulates cells to divide. EGF exerts its actions by binding to the EGFR, a 170 kDa protein. Epidermal growth factor is also a key growth factor regulating cell survival. Through its binding to cell surface receptors, EGF activates an extensive network of signal transduction pathways that include activation of the PI3K/AKT, RAS/ERK and JAK/STAT pathways

NCBI Gene ID

25313

Swiss Prot

P07522

Accession Number

P07522

Host

Rabbit

Reactivity

Rat

Immunogen

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant Rat EGF (Rat Epidermal Growth Factor) . Rat EGF specific antibody was purified by affinity chromatography and then biotinylated.

Clonality

Polyclonal

Conjugation

Biotin

Type

Primary Antibodies, Antibody Pairs

Field of Research

Growth Factors

Concentration

Batch dependent

Modification

None

Shipping Conditions

Room Temp

Storage Conditions

AntiEGF antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=38-211

Symbol

Egf

NCBI Official Name

Epidermal growth factor

NCBI Organism

Rattus norvegicustus norvegicus

Other Product Names

Pro-epidermal growth factorEGF

Tested Applications

ELISA, WB

Protein ID

1352360

Physical Properties

Lyophilized

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