Nanog Antibody
Product Specifications
Background
Nanog is a newly identified homeodomain-bearing transcriptional factor. Nanog expression is specific to early embryos and pluripotential stem cells including mouse and human embryonic stem (ES) and embryonic germ (EG) cells. It is a key molecule involved in the signaling pathway for maintaining the capacity for self-renewal and pluripotency, bypassing regulation by the STAT3 pathway. Nanog mRNA is present in pluripotent mouse and human cell lines, and absent from differentiated cells. Nanog-deficient ES cells lose pluripotency and differentiate into extraembryonic endoderm lineage. Thus it is one of the molecular markers suitable for recognizing the undifferentiated state of stem cells in the mouse and human.
NCBI Gene ID
79923
Swiss Prot
Q9H9S0
Accession Number
Q9H9S0
Host
Rabbit
Reactivity
Human
Immunogen
Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hNanog. Human Nanog specific antibody was purified by affinity chromatography employing immobilized hNanog matrix.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies, Antibody Pairs
Field of Research
Cancer
Purification
Nanog antibody was purified by affinity chromatography employing immobilized Nanog matrix.
Concentration
Batch dependent
Modification
None
Shipping Conditions
Room Temp
Storage Conditions
Nanog antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=38-108
Symbol
NANOG
NCBI Official Name
Nanog homeobox
NCBI Organism
Homo sapiens
Other Product Names
Homeobox protein NANOG, Homeobox transcription factor Nanog, hNanog
Tested Applications
ELISA, WB
Protein ID
118573073
Physical Properties
Lyophilized
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