NFATc1 Antibody
Product Specifications
Background
NFATc1 plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 or IL-4 gene transcription. It controls gene expression in embryonic cardiac cells. Regulates not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells.
NCBI Gene ID
4772
Swiss Prot
O95644
Accession Number
8928220
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant N-terminal human NFATc1 fragment fused to a GST-tag.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies, Functional Antibodies
Field of Research
Cancer, Immunology, Innate Immunity, Stem Cell
Purification
Antigen affinity purified.
Concentration
500 ug/ml
Buffer
Liquid. In PBS containing 1mg/ml BSA and 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C.
Specificity
Recognizes all known human NFATc1 isoforms.
Applications Notes
Functional Application: Induces apoptosis with or without cross-linking (Protein A), depending on cell type. Note: Optimal conditions must be determined.
Symbol
NFATC1
NCBI Official Name
Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NCBI Organism
Homo sapiens
Other Product Names
Nuclear Factor of Activated T Cells; Cytoplasmic 1; NFAT Transcription Complex Cytosolic Component; NF-ATc1
Tested Applications
Functional Assays, ICC, IHC, IP, WB
Protein ID
O95644
Physical Properties
Liquid
Frequently Asked Questions
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