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NFATc1 Antibody

Product Specifications

Background

NFATc1 plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 or IL-4 gene transcription. It controls gene expression in embryonic cardiac cells. Regulates not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells.

NCBI Gene ID

4772

Swiss Prot

O95644

Accession Number

8928220

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant N-terminal human NFATc1 fragment fused to a GST-tag.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies, Functional Antibodies

Field of Research

Cancer, Immunology, Innate Immunity, Stem Cell

Purification

Antigen affinity purified.

Concentration

500 ug/ml

Buffer

Liquid. In PBS containing 1mg/ml BSA and 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Stable for at least 1 year after receipt when stored at -20˚ C.

Specificity

Recognizes all known human NFATc1 isoforms.

Applications Notes

Functional Application: Induces apoptosis with or without cross-linking (Protein A), depending on cell type. Note: Optimal conditions must be determined.

Symbol

NFATC1

NCBI Official Name

Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

NCBI Organism

Homo sapiens

Other Product Names

Nuclear Factor of Activated T Cells; Cytoplasmic 1; NFAT Transcription Complex Cytosolic Component; NF-ATc1

Tested Applications

Functional Assays, ICC, IHC, IP, WB

Protein ID

O95644

Physical Properties

Liquid

Frequently Asked Questions

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