CARMA1 Antibody
Product Specifications
Background
CARMA1 is involved in the costimulatory signal essential for T cell receptor (TCR) -mediated T cell activation. Its binding to DPP4 induces T cell proliferation and NF-kappaB activation in a T cell receptor/CD3-dependent manner. CARMA1 activates NF-kappaB via Bcl10 and IKK.
NCBI Gene ID
84433
Swiss Prot
Q9BXL7
Accession Number
16507952
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
N-terminal human CARMA1 (aa 1-221 containing the CARD domain) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Innate Immunity
Concentration
1 mg/ml
Buffer
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C.
Specificity
Recognizes human and mouse CARMA1. Detects a band of ~130Dka by Western blot.
Applications Notes
Western Blot: (1ug/ml) .
Symbol
CARD11
NCBI Official Name
Caspase recruitment domain family, member 11
NCBI Organism
Homo sapiens
Other Product Names
CARD11; Bimp3; Caspase Recruitment Domain-containing Protein 11; CARD-containing MAGUK Protein 1
Tested Applications
ICC, IHC, WB
Protein ID
NP_115791.2
Physical Properties
Liquid
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