IL-37 Antibody
Product Specifications
Background
IL-37 (Interleukin-37) belongs to the IL-1 family. It binds to interleukin-18 receptor (IL-18R) but not to IL-1 receptor. It was shown to play an important role as a link between innate and adaptive immunity and it is suggested as a new player in the inflammatory and immune responses mediated by the IL-18/IL-18R axis. It was also shown to inhibit tumor growth.
NCBI Gene ID
27178
Swiss Prot
Q9NZH6
Accession Number
20127524
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human IL-37.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Innate Immunity, Obesity
Concentration
1 mg/ml
Buffer
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Stable for at least 6 months after receipt when stored at -20˚ C.
Specificity
Recognizes human IL-37. Detects a band of ~30kDa by Western blot.
Applications Notes
ELISA: (direct and indirect: 1:2,000-1:5,000), Immunohistochemistry: (1:50) Immunoprecipitation: (1:500- 1:2,000) . Western Blot: (1:2,000-1:5,000 using ECL; suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk; suggested incubation time is 1 hour at room temperature) . Optimal conditions must be determined individually for each application.
Symbol
IL37
NCBI Official Name
Interleukin 37
NCBI Organism
Homo sapiens
Other Product Names
Interleukin-1 Family Member 7; IL-1F7; FIL1 zeta; IL-1X; Interleukin-1 Homolog 4; IL-1H4; Interleukin-1 zeta; IL-1 zeta; IL-1RP1; IL1F7; FIL1Z, IL1H4, IL1RP1
Tested Applications
ELISA, IHC, IP, WB
Protein ID
NP_055254
Physical Properties
Liquid
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