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FGF-21 Antibody

Product Specifications

Background

FGF-21 stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression) . Activity requires the presence of bKlotho.

NCBI Gene ID

26291

Swiss Prot

Q9NSA1

Accession Number

9506597

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant human FGF-21.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity

Concentration

1 mg/ml

Buffer

Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Stable for at least 6 months after receipt when stored at -20˚ C.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=36-277

Specificity

Recognizes human and mouse FGF-21. Detects a band of ~25kDa by Western blot.

Applications Notes

ELISA: (direct and indirect: 1:2,000-1:5,000) . Immunohistochemistry: (paraffin sections 1:2,000-1:5,000) . Western Blot: (1:2,000-1:5,000 using ECL; suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk; suggested incubation time is 1 hour at room temperature) . Optimal conditions must be determined individually for each application.

Symbol

FGF21

NCBI Official Name

Fibroblast growth factor 21

NCBI Organism

Homo sapiens

Other Product Names

Fibroblast Growth Factor 21

Tested Applications

ELISA, IHC, WB

Protein ID

NP_061986.1

Physical Properties

Liquid

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