Resistin Antibody (biotin)
Product Specifications
Background
The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
NCBI Gene ID
56729
Swiss Prot
Q9HD89
Accession Number
9966777
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human resistin.
Clonality
Polyclonal
Conjugation
Biotin
Type
Primary Antibodies
Field of Research
Obesity
Concentration
1 mg/ml
Buffer
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Stable for at least 6 months after receipt when stored at -20˚ C.
Specificity
Recognizes human resistin. Weakly cross-reacts with mouse resistin. Detects a band of ~10kDa by Western blot.
Applications Notes
ELISA: (direct and indirect: 1:5,000-1:10,000) . Western Blot: (1:2,000-1:10,000 using ECL. Suggested blocking and dilution buffer is TBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature) . Optimal conditions must be determined individually for each application.
Symbol
RETN
NCBI Official Name
Resistin
NCBI Organism
Homo sapiens
Other Product Names
FIZZ3; Found in Inflammatory Zone 3; ADSF; Adipose Tissue-Specific Secretory Factor
Tested Applications
ELISA, WB
Protein ID
NP_065148.1
Physical Properties
Liquid
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