Bmf Antibody [9G10]
Product Specifications
Background
Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.
NCBI Gene ID
90427
Swiss Prot
Q96LC9
Accession Number
15723378
Host
Rat
Reactivity
Human, Mouse
Immunogen
Recombinant mouse Bmf.
Clonality
Monoclonal
Clone
9G10
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Immunology
Purification
>95% (SDS-PAGE)
Concentration
1 mg/ml
Buffer
Liquid. In PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C.
Fragment
IgG2a, kappa
Specificity
Recognizes human and mouse Bmf. Detects several cross-reactivity bands of unknown identity in mice by western blot.
Applications Notes
Flow Cytometry: (overexpressed in cell lines) . Immunoprecipitation: (1-5ug/ml) . Western Blot: (1-2ug/ml) .
Symbol
BMF
NCBI Official Name
Bcl2 modifying factor
NCBI Organism
Homo sapiens
Other Product Names
Bcl-2-modifying Factor
Tested Applications
Flow, IP, WB
Protein ID
NP_277038
Physical Properties
Liquid
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