Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

PARP-10 Antibody [5H11]

Product Specifications

Background

PARP-10. PARP-10 mono (ADP-ribosyl) ates (MARylates) NEMO (NF-kappaB essential modulator), which results in reduced NEMO polyubiquitylation and thus decreased NF-kappaB signaling. Overexpression of PARP-10 was shown to lead to apoptosis. PARP-10 knockdown leads to increased cell survival. Additional substrates of PARP-10, such as GSK-3beta were identified and PARP-10-mediated mono (ADP-ribosyl) ation (MARylation) was shown to be involved in regulating multiple processes, including Wnt signaling.

NCBI Gene ID

84875

Swiss Prot

Q53GL7

Accession Number

116248563

Host

Rat

Reactivity

Human

Immunogen

Recombinant human PARP-10 [ARTD10] (aa 1-907) fused to a GST-tag.

Clonality

Monoclonal

Clone

5H11

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer, Innate Immunity, Obesity

Concentration

Batch dependent

Buffer

Liquid. Cell culture supernatant containing RPMI, 10% FCS and 0.05% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Stable for at least 1 year after receipt when stored at +4˚ C.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=36-172

Fragment

IgG1

Specificity

Recognizes human PARP-10 [ARTD10] with an epitope between aa 256-407, containing the glycine rich (G-rich) region.

Applications Notes

Immunocytochemistry: (1:50-1:200) . Immunoprecipitation: (1:10) . Western Blot: (1:50) . Optimal conditions must be determined individually for each application.

Symbol

PARP10

NCBI Official Name

Poly (ADP-ribose) polymerase family member 10

NCBI Organism

Homo sapiens

Other Product Names

ADP-ribosyltransferase Diphtheria Toxin-like 10; Poly (ADP-ribose) Polymerase-10

Tested Applications

ICC, IP, WB

Protein ID

Q53GL7

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

4-Bromo-3-methoxy-N-methylbenzamide
OR1059642-01 100 mg

4-Bromo-3-methoxy-N-methylbenzamide

Ask
View Details
4-Bromo-3-methoxy-N-methylbenzamide
OR1059642-02 250 mg

4-Bromo-3-methoxy-N-methylbenzamide

Ask
View Details
4-Bromo-3-methoxy-N-methylbenzamide
OR1059642-03 1 g

4-Bromo-3-methoxy-N-methylbenzamide

Ask
View Details
A-1 Microglobulin 5+1
A06603H 2x 25 mL Buffer + 1x 10 mL Latex

A-1 Microglobulin 5+1

Ask
View Details
Rabbit Polyclonal TATDN1 Antibody [PE]
NBP2-97967PE 0.1 mL

Rabbit Polyclonal TATDN1 Antibody [PE]

Ask
View Details
KAT5 (NM_006388) Human Over-expression Lysate
LC401920 20 µg

KAT5 (NM_006388) Human Over-expression Lysate

Ask
View Details