Neutrophils Antibody [Nimp-R14] (biotin)

Product Specifications

Background

Neutrophils are key components of the inflammatory response and as such contribute to the killing of microorganisms. In addition, recent evidence suggests their involvement in the development of the immune response. The Nimp-R14 mAb displays features of an optimal reagent allowing the selective depletion of mouse neutrophils in vivo.

NCBI Gene ID

546644

Swiss Prot

P35461

Accession Number

547876

Host

Rat

Reactivity

Mouse

Immunogen

Purified mouse BALB/c neutrophils.

Clonality

Monoclonal

Clone

Nimp-R14

Conjugation

Biotin

Type

Primary Antibodies, Functional Antibodies

Field of Research

Immunology, Innate Immunity

Purification

>95% (SDS-PAGE)

Concentration

0.5 mg/ml

Buffer

Liquid. In PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Stable for at least 1 year after receipt when stored at -20˚ C.

Fragment

IgG2b

Specificity

Recognizes mouse neutrophils (surface protein mouse Ly-6G) .

Applications Notes

Flow Cytometry: (1:100) . Immunohistochemistry: (1:200; frozen section / paraffin section) . Immunocytochemistry: (1:200) . Functional (Blocking) : 250ug / mouse (Optimal reagent to deplete neutrophils in vivo) .