TRAIL-R3 Antibody [TR3.06]
Product Specifications
Background
TRAIL-R3 is a receptor for the cytotoxic ligand TRAIL. It lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
NCBI Gene ID
8794
Swiss Prot
O14798
Accession Number
2338421
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human TRAIL-R3 (DcR1) .
Clonality
Monoclonal
Clone
TR3.06
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology
Purification
>95% (SDS-PAGE)
Concentration
1 mg/ml
Buffer
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=36-139
Fragment
IgG1
Specificity
Recognizes human TRAIL-R3. Does not cross-react with human TRAIL-R1, -R2 or -R4.
Applications Notes
Immunohistochemistry: (paraffin sections) (20ug/ml) . Western Blot: (1ug/ml) . Optimal conditions must be determined individually for each application.
Symbol
TNFRSF10C
NCBI Official Name
Tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
NCBI Organism
Homo sapiens
Other Product Names
TRAIL Receptor 3; DcR1; TRID; TNFRSF10C; CD263
Tested Applications
Flow, IHC, WB
Protein ID
AF012536
Physical Properties
Liquid
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