TRAIL-R3 Antibody [HS301]
Product Specifications
Background
TRAIL-R3 is a receptor for the cytotoxic ligand TRAIL. It lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
NCBI Gene ID
8794
Swiss Prot
O14798
Accession Number
2338421
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human TRAIL-R3 (DcR1) .
Clonality
Monoclonal
Clone
HS301
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology
Purification
>95% (SDS-PAGE)
Concentration
1 mg/ml
Buffer
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C.
Fragment
IgG1
Specificity
Recognizes human TRAIL-R3. Does not cross-react with human TRAIL-R1, -R2 or -R4.
Applications Notes
Definition for 1 test: 1ul of labeled antibody in 200ul of Flow Cytometry buffer (see online protocol) .
Symbol
TNFRSF10C
NCBI Official Name
Tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
NCBI Organism
Homo sapiens
Other Product Names
TRAIL Receptor 3; DcR1; TRID; TNFRSF10C; CD263
Tested Applications
Flow, ICC
Protein ID
AF012536
Physical Properties
Liquid
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