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TRAIL-R3 Antibody [HS301]

Product Specifications

Background

TRAIL-R3 is a receptor for the cytotoxic ligand TRAIL. It lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.

NCBI Gene ID

8794

Swiss Prot

O14798

Accession Number

2338421

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human TRAIL-R3 (DcR1) .

Clonality

Monoclonal

Clone

HS301

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology

Purification

>95% (SDS-PAGE)

Concentration

1 mg/ml

Buffer

Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Stable for at least 1 year after receipt when stored at -20˚ C.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=36-134

Fragment

IgG1

Specificity

Recognizes human TRAIL-R3. Does not cross-react with human TRAIL-R1, -R2 or -R4.

Applications Notes

Definition for 1 test: 1ul of labeled antibody in 200ul of Flow Cytometry buffer (see online protocol) .

Symbol

TNFRSF10C

NCBI Official Name

Tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain

NCBI Organism

Homo sapiens

Other Product Names

TRAIL Receptor 3; DcR1; TRID; TNFRSF10C; CD263

Tested Applications

Flow, ICC

Protein ID

AF012536

Physical Properties

Liquid

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