ANGPTL7 Antibody [Kairos 108-4]

Product Specifications

Background

ANGPTL7 is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterized as a potent target gene of the WNT/ beta-catenin signaling pathway, and is a pharmacogenomics target in the fields of oncology and regenerative medicine. Overexpression of ANGPTL7 increases collagen expression and might exert a pathogenic role in glaucoma.

NCBI Gene ID

10218

Swiss Prot

O43827

Accession Number

62899821

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human full length ANGPTL7.

Clonality

Monoclonal

Clone

Kairos 108-4

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Stem Cell

Concentration

1 mg/ml

Buffer

Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Stable for at least 1 year after receipt when stored at -20˚ C.

Fragment

IgG1, kappa

Specificity

Recognizes human ANGPTL7. Detects a band of ~45kDa by Western blot. Weakly cross-reacts with human ANGPTL7-CCD.

Applications Notes

ELISA: (direct or indirect: 1:2,000-1:5,000) . Immunohistochemistry: (paraffin sections (1:100) ) . Western blot: (1:2,000-1:5,000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature) . Optimal conditions should be determined individually for each application.