Jagged-1 Antibody [J1G53-3] (FITC)
Product Specifications
Background
Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro) . Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF) .
NCBI Gene ID
182
Swiss Prot
P78504
Accession Number
4557679
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human Jagged-1.
Clonality
Monoclonal
Clone
J1G53-3
Conjugation
FITC
Type
Primary Antibodies
Field of Research
Cancer
Concentration
1 mg/ml
Buffer
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C.
Fragment
IgG1, kappa
Specificity
Recognizes human Jagged-1. Detects a band of ~180kDa by Western blot.
Applications Notes
Flow Cytometry: (1:20-1:100) . Optimal conditions should be determined individually for each application.
Symbol
JAG1
NCBI Official Name
Jagged 1
NCBI Organism
Homo sapiens
Other Product Names
Protein Jagged-1; CD339; JAG1
Tested Applications
Flow
Protein ID
NP_000205
Physical Properties
Liquid
Curated Selection
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