Vaspin Antibody [VP63]
Product Specifications
Background
Vaspin (Visceral adipose tissue-derived serpin; Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing adipocytokine that has been isolated from both visceral and subcutaneous white adipose tissue. Based on recent findings, vaspin is suggested to regulate immune responses and inflammation and was found to be correlated with various metabolic parameters. Vaspin may represent a novel biomarker for obesity and impaired insulin sensitivity and might serve as a newtherapeutic target of metabolic syndrome.
NCBI Gene ID
145264
Swiss Prot
Q8IW75
Accession Number
27777657
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human vaspin.
Clonality
Monoclonal
Clone
VP63
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Innate Immunity, Obesity
Concentration
1 mg/ml
Buffer
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C.
Fragment
IgG1, kappa
Specificity
Recognizes human vaspin. Detects a band of ~48kDa by Western blot.
Applications Notes
ELISA: (direct or indirect: 1:2,000-1:5,000) . Western blot: (1:2,000-1:5,000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature) . Optimal conditions should be determined individually for each application.
Symbol
SERPINA12
NCBI Official Name
Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
NCBI Organism
Homo sapiens
Other Product Names
Visceral Adipose Tissue-derived Serine Protease Inhibitor; Serpin A12; OL-64
Tested Applications
ELISA, WB
Protein ID
NP_776249.1
Physical Properties
Liquid
Frequently Asked Questions
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