ACE2 Antibody [AC384]

Product Specifications

Background

ACE2 has direct effects on cardiac functions. It is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE2 converts angiotensin I to angiotensin 1-9. ACE2 was also identified as a functional receptor for SARS coronavirus.

NCBI Gene ID

59272

Swiss Prot

Q9BYF1

Accession Number

11225609

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human ACE2.

Clonality

Monoclonal

Clone

AC384

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Innate Immunity, Obesity

Concentration

1 mg/ml

Buffer

Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Stable for at least 1 year after receipt when stored at -20˚ C.

Fragment

IgG1, kappa

Specificity

Recognizes human ACE2.

Applications Notes

ELISA: (direct or indirect: 1:2,000-1:10,000) . Western blot: (1:2,000-1:10,000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature) . Optimal conditions should be determined individually for each application.