GITR Antibody [AIT 158D]

Product Specifications

Background

GITR is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediates NF-kappaB activation via the TRAF2/NIK pathway.

NCBI Gene ID

8784

Swiss Prot

Q9Y5U5

Accession Number

4759246

Host

Rat

Reactivity

Human

Immunogen

Recombinant human GITR.

Clonality

Monoclonal

Clone

AIT 158D

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology

Concentration

1 mg/ml

Buffer

Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Stable for at least 1 year after receipt when stored at -20˚ C.

Fragment

IgG2a, kappa

Specificity

Recognizes human GITR. Does not cross-react with mouse GITR.

Applications Notes

ELISA: (direct and indirect: 1:5,000-1:10,000) . Flow Cytometry: (1:1,000) . Optimal conditions must be determined individually for each application.

Symbol

TNFRSF18

NCBI Official Name

Tumor necrosis factor receptor superfamily, member 18

NCBI Organism

Homo sapiens

Other Product Names

Tumor Necrosis Factor Receptor Superfamily Member 18; Activation-inducible TNFR Family Receptor; Glucocorticoid-induced TNFR-related Protein; CD357; TNFRSF18; AITR