Resistin Antibody [RRES 07]
Product Specifications
Background
The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
NCBI Gene ID
246250
Swiss Prot
Q8K4J7
Accession Number
81866779
Host
Mouse
Reactivity
Rat
Immunogen
Recombinant rat resistin.
Clonality
Monoclonal
Clone
RRES 07
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity
Concentration
1 mg/ml
Buffer
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=36-014
Fragment
IgG1, kappa
Specificity
Recognizes rat resistin. Detects a band of ~10kDa by Western blot. Does not cross-react with human and mouse resistin.
Applications Notes
ELISA: (direct or indirect: 1:5,000-1:10,000) . Western blot: (1:2,000-1:10,000 using ECL. Suggested blocking and dilution buffer is TBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature) . Optimal conditions should be determined individually for each application.
Symbol
Retn
NCBI Official Name
Resistin
NCBI Organism
Rattus norvegicus
Other Product Names
FIZZ3; Found in Inflammatory Zone 3; ADSF; Adipose Tissue-Specific Secretory Factor
Tested Applications
ELISA, WB
Protein ID
Q8K4J7
Physical Properties
Liquid
Curated Selection
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