Resistin Antibody [MRES 06]
Product Specifications
Background
The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
NCBI Gene ID
57264
Swiss Prot
Q99P87
Accession Number
12667798
Host
Rat
Reactivity
Mouse
Immunogen
Recombinant mouse resistin.
Clonality
Monoclonal
Clone
MRES 06
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity
Concentration
1 mg/ml
Buffer
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=36-003
Fragment
IgG2a, kappa
Specificity
Recognizes mouse resistin. Detects a band of ~14kDa by Western blot. Does not cross-react with human resistin.
Applications Notes
ELISA: (direct or indirect: 1:5,000-1:10,000) . Western blot: (1:5,000-1:10,000 using ECL. Suggested blocking and dilution buffer is TBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature) . Optimal conditions should be determined individually for each application.
Symbol
Retn
NCBI Official Name
Resistin
NCBI Organism
Mus musculus
Other Product Names
FIZZ3; Found in Inflammatory Zone 3; ADSF; Adipose Tissue-Specific Secretory Factor
Tested Applications
ELISA, WB
Protein ID
NP_075360.1
Physical Properties
Liquid
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