CCNB1 Antibody

Product Specifications

Background

The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34 (cdc2) to form the maturation-promoting factor (MPF) . Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq].

NCBI Gene ID

891

Swiss Prot

P14635

Accession Number

P14635

Host

Rabbit

Reactivity

Human

Immunogen

This CCNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-268 amino acids from the Central region of human CCNB1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat, Zebrafish, Hamster, B

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Symbol

CCNB1

NCBI Official Name

G2/mitotic-specific cyclin-B1

NCBI Organism

Homo sapiens

Background Reference 01

Kreis, N.N., et al. Oncogene 29 (41) :5591-5603 (2010)

Background Reference 02

Van Zon, W., et al. J. Cell Biol. 190 (4) :587-602 (2010)

Background Reference 03

Harley, M.E., et al. EMBO J. 29 (14) :2407-2420 (2010)

Background Reference 04

Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :

Other Product Names

G2/mitotic-specific cyclin-B1, CCNB1, CCNB

Tested Applications

WB, IHC-P

Protein ID

116176

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

124944 100 µg

CHIA (Acidic Mammalian Chitinase, AMCase, Lung-specific Protein TSA1902)

Ask

View Details

NBP1-88027PEP 0.1 mL

Vitamin D BP Recombinant Protein Antigen

Ask

View Details

TR711285 1 Kit

Dynlt1 Rat shRNA Plasmid (Locus ID 83462)

Ask

View Details

GA216442 1 Kit

Mouse Lrrc58 activation kit by CRISPRa

Ask

View Details

132095-ML490 100 µL

Securin-2 (Pituitary Tumor-transforming Gene 2 Protein, PTTG2) (MaxLight 490)

Ask

View Details